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In the present study, we fed thirty young Wistar rats that were in the secondary sexual characteristic period on calcium deficient diet so the osteoporotic mandible, which was thought as a reason for the declining of masticatory force and masticatory ability, was resulted in. After that we researched the effect of dietary therapy on the matrix formation of these osteoporotic mandible. The high calcium diet was made from sea shell, called UNICALO. The results were shown as follows. 1. Microphotometric findings Significant differences were observed between the control group, calcium deficient ・ standard diet group, calcium deficient・UNICALO group and low calcium -UNICAL@ group (p <O.Ol). And significant differences were also observed between control group and low calcium・standard diet group (p<O.05). 2. X-ray microanalysis of Ca and P By surface microanalysis, it has been found that density of calcium was higher than phosphorus in any group. Significant differences were found in quantitative analysis which was done by calculating the calcium and phosphorus relative proportion against control group, showed as Ca/[Ca]c and P/[P]c. The results of Cal[Ca]c were calcium deficient・ staridard diet group<calcium deficient・UNICAL@ group<low calcium・UNICALO group<low ¢ alcium ・ standard diet group< control group, while P/[P]c showed as centrol< calciurn deficient・ standard diet group<calcium deficient・ UNICALO group<low calciurn +standard diet group<low calcium ・ UNICAL@ group. 3. Histopathological findings As contrasted with control group, the enlargement of bone marrow space, the number and thickness of trabeculae decreasing were obvious in calcium deficient-standard diet group. Bone osteopenia were obviously seen such as decrease of the number of lamellae and lacunae. Cornpared with calcium deficient standard diet group, the calcium deficient・UNICALO group showed that bone marrow space decreased and bone rernolding was active, but the number of

An Experimental Study of Dietary Therapy on Osteoporotic Mandibular Alveolus in Young Rats : On Bone Matrix Formation