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The objective of the present study is to determine the anti-obesity effects of Akkermansia munciniphila on some biometric measurements. 40 patients were divided into two groups, each with 20 patients; G1 group consumed the probiotic of A. munciphila and G2 consumed placebo capsules. The results showed significant effects on the body weight (p≤ 0.001), which was reduced by a range of 2.29 to -0.7, whereas non-significant differences were observed in the Waist circumferance . The study also showed significant differences (p≤0.001) between the two groups in the levels of cholesterol (287 vs. 285 mg/dl) , whereas the level of Triglyceride significantly decreased in the treated patients (p≤0.001). No significant differences were observed in the concentration of fat. There were also significant differences in the levels of fetuin-A (p≤0.020) and serotonin ( p≤ 0.039 ). The consumption of the probiotic of A. muciniphila was proved to be beneficial for human health, while further studies are needed to explore more effects.

The Effects of Akkermansia Munciniphila on Serotonin and Fetuin-A Hormone Levels and Some Biometric Parameters in Obese Patients