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HbA1c levels decreased with increasing Hb levels, independent of age, sex, BMI, FPG, and smoking and alcohol habits in Japanese men and women without diabetes or anemia. There was an interaction between sex and hemoglobin in the effects on HbA1c. The interpretation of HbA1c values should be cautious in the screening of glucose intolerance.

Effect of Hemoglobin Levels and Sex on HbA1c Levels among Japanese Population