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Background: Celiac disease is an immune-mediated mucosal disorder primarily affecting the small intestine in genetically-susceptible individuals. It may be triggered by dietary exposure to gluten. In some patients, extra-intestinal or autoimmune changes may occur, as hepatobiliary, neurological, or endocrine disorders. The aim to study the reproductive health indicators among Sudanese female with celiac disease (15-45 years) and to determine menstrual pattern, infertility status as well as obstetrical outcome among those women at Ibn sina specialized hospital from December 2014 to June 2015. Material and Methods: This is a descriptive analytic hospital based study, carried out at Ibn sina specialized hospital, conducted from December 2014 to June 2015, included 81 women, diagnosed as celiac disease, attended celiac clinic during the study period. The data was collected using a questionnaire by me after agreed informative consent and analyzed by computer using SPSS program (20). Results: 32 (39.5%) of women were between 25-34 years and 58 (71.6%) of women were on strict gluten diet. 52 (64.1%) of women had menarche after age of 16, 30 (37%) experienced oligomenorrhoea and 2 (2.5%) had secondary amenorrhoea and their menstrual pattern was improved with gluten free diet (P value 0.002), 36 (44.4%) of women were married, 21 (58.3%) of these women experienced difficulty in conceiving which affected by the duration of their disease(P value 0.000), 23 (63.9%), 21(58.3%) had past history of miscarriage and pregnancy induced hypertension respectively. Conclusion: celiac disease has a significant role in women reproductive health, in the form of delay menarche, a change of menstrual pattern, difficulty in conceiving, and poor obstetric outcome such as miscarriage and pregnancy induced hypertension.

Reproductive Health Indicators Among Women with Celiac Disease in Sudan at Ibn Sina Specialized Hospital from December 2014 to June 2015