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Schmidt Syndrome refers to the combination of autoimmune adrenal insufficiency (Addison’s disease) with autoinmune thyroiditis, and is part of a larger syndrome known as autoinmune polyendocrine syndrome type II or polyglandular autoinmune syndrome type II (PAS II). Schmidt Syndrome as a 1:20,000 prevalence in general population with 3:1 ratio of females to males affected. It is autosomal dominant inheritance with variable penetrance. Associated with certain HLA antigens HLA-DR3, HLA-DR4, non HLA gene M-ICA and CTLA-4. The diagnosis of the Schmidt Syndrome is the same as that of the individual disorders. The treatment includes of primary hypothyroidism and the Addison disease. We present the evolution, the clinic and the treatment of a patient diagnosed with Schmidt Syndrome.

Debut of Polyglandular Autoimmune Syndrome Type 2 (Schmidt Syndrome) in a Patient with Chronic Kidney Disease of Unknown Etiology in Peritoneal Dialysis