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The influence of glutathione on the prooxidant-antioxidant balance in rats’ kidneys and blood under the conditions of rhabdomyolytic model of acute kidney injury was studied in the experiment. It is observed that intraperitoneal administration of glutathioneіn dose 30 mg/kg normalizes the prooxidant-antioxidant balance, confirmed by the reduction of lipid and protein peroxidation intensity, normalization of catalase and glutathione peroxidase activity, SH-groups аndceruloplasmin content.

The influence of glutathione on the prooxidant-antioxidant activity in kidneys and blood of rats with rhabdomyolytic model of acute kidney injury