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In the conditions of the growth of morbidity and mortality rates from enteritis of the viral origin in children, in particular rotavirus enteritis (RE), a special attention is paid to optimization of the cost for pharmacotherapy, and forecasting of possible expenses for the treatment and preventive vaccination of RE in children. Aim. To conduct the “budget impact” analysis of pharmacotherapy and preventive vaccination of RE in children in Ukraine in 2017-2018 and predict the amount of compensation for drugs by two of the approaches to the management of the disease for 2018. Materials and methods. The method of the “budget impact” pharmacoeconomic analysis, graphical, analytical and methods of mathematical modeling, Statistica 6 software were used. Results. The impact on the budget due to the introduction of vaccination among children requires more costs than pharmacotherapy, namely the ratio of costs in the first year – 1:30, in the second year – 1:10. The predicted volume of vaccination compensation in Ukraine is 772,952,274 UAH (711 UAH per a child), compensation for the cost of drugs for the treatment of RE – 3560,853 UAH. (281.49 UAH per a patient). Conclusions. It has been found that there is a significant economic burden of vaccination on the budget; however, this method has the benefits delayed in time. The predicted total volume of compensation (reimbursement) of vaccination is significantly higher than the volume of compensation of the RE pharmacotherapy. However, the cost of vaccination per capita exceeded by 2.5 times compared to the treatment.

Pharmacoeconomic approaches to forecasting of the budget impact and compensation for rotavirus enteritis in children in Ukraine