English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The biology of fibroblast-like cells is important in understanding of pathogeneis of rheumatoid arthritis (RA). Fibroblast-like synovial cells (FLSs) is major component of pannus in inflamed joint, and mesenchymal stromal cells (MSCs) is thought to be in bone edema, a recently reported RA lesion in bone marrow that is detectable by MRI. It is interesting that MSCs share many characteristics with FLSs. Both types of cells can secrete cytokines, and differentiate into mesenchymal lineage cells such as osteoblasts, chondrocytes, and adipocytes. In this review, we discuss the possible contribution of the adipogenesis insufficency of FLSs or MSCs to the development of synovial hyperplasia and bone edema in RA. Rec.12/28/2011, Acc.4/4/2012, pp202-207

inflammation and regeneration

Functional change of synoviocytes and mesenchymal stromal cells through adipogenesis: A possible model of pannus and bone edema formation in rheumatoid arthritis