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Macrodystrophia lipomatosa (MDL) is a rare congenital non-hereditary condition characterised by an abnormal overgrowth of mesenchymal tissue of a digit or an extremity. Although MDL is interchangeably described by terms such as macrodactyly and macrosomia, the entity has to be differentiated from other acquired and hereditary causes of macrodactyly. Rare association with osteochondromas and lipomas in other parts of the body has also been reported. We present a case with gradual progressive swellings of the right great toe and right thigh, which was diagnosed to be a case of MDL of the great toe with fibrolipomatous hamartoma of medial plantar nerve and lipomatosis of the thigh based on characteristic imaging findings.

Macrodystrophia lipomatosa with fibrolipomatous hamartoma of medial plantar nerve and lipomatosis of thigh