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The number of elderly patients diagnosed with cancer has increased. There are no studies that assess the oncological results in elderly patients with retroperitoneal sarcomas. The purpose of this study was to define the demographic characteristics and prognostic factors in elderly patients with retroperitoneal sarcomas. Methods: A retrospective study including 25 elderly patients (> 65 years) diagnosed with retroperitoneal sarcomas at the National Institute of Cancerology (Mexico). Demographic variables and prognostic factors were analyzed. Results: Twenty-five patients, 16 men (64%) and 9 women (36%) with a median age of 69.3 years (65-82 years). Tumor size average of 24.4 cm (8-61 cm); 19 patients (76%) had high-grade tumors, the most frequent histological type was liposarcoma. Overall-survival was 34.6 months (95% CI: 20.86-48.40) for patients with ECOG < 1 and 3.44 months (95% CI: 1.68-5.2) for those with ECOG > 1. In the multivariate analysis, the performance status measured by ECOG (p < 0.001), the presence of comorbidities (p = 0.038) and the presence of resections with macroscopic residual disease (p < 0.001) were associated with lower overall-survival. Conclusion: Age should not be a limitation to determine which group of patients are those who should not undergo an oncological treatment; performance status and the presence of comorbidities are prognostic factors that should be considered in elderly patients with retroperitoneal sarcomas.

Oncological results of elderly patients undergoing surgery for retroperitoneal sarcomas