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The role of serotonin transporter and its functional gene polymorphism (5-HTTLPR, serotonin transporter linked polymorphic region) was investigated in sleep disturbances in various mental disorders, with conflicting findings. Here, the association of particular sleep disturbances with 5-HTTLPR genotypes and platelet serotonin (5-HT) concentration was determined simultaneously in veterans with posttraumatic stress disorder (PTSD), who were subdivided into those with or without comorbid depression.

psychiatria danubina

THE ASSOCIATION BETWEEN SEROTONIN TRANSPORTER POLYMORPHISM, PLATELET SEROTONIN CONCENTRATION AND INSOMNIA IN NON-DEPRESSED VETERANS WITH POSTTRAUMATIC STRESS DISORDER