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Correspondence to: Dr. Takahiro Kanno, Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, Izumo, Shimane, 693-8501 Japan; Tel: +81-853-20-2301; Fax: +81-853-20-2299; E-mail: tkanno@med.shimane-u.ac.jp Abstract: The aim of this retrospective clinical study was to evaluate the applicability of newly developed uncalcined and unsintered hydroxyapatite (u-HA) particles and poly-L-lactide (PLLA; u-HA/PLLA) composite sheets with tack fixation for navigation-assisted orbital fracture reconstruction. Osteosynthetic bone fixation and reconstruction systems made from u-HA/PLLA composites have recently drawn attention for effective application in maxillofacial bone surgery because of their osteoconductive properties and bioresorbability. One limitation of these systems in the clinical setting, however, is the complicated drill hole tapping that is required for screw fixation. Herein, we report the feasible application of a u-HA/PLLA sheet with tack fixation for intraoperative navigation-assisted orbital wall reconstruction; this approach may be suitable for fragile and anatomically complicated periorbital-maxillofacial bony regions. The study included 9 patients (mean age, 46.6 years) with moderate and medium complexity to large and high complexity orbital wall defects (3 type II defects and 6 type III). The mean follow-up period was 8.9 months (range, 6 to 18 months). Overall, the application of the u-HA/PLLA sheet with tack fixation gave excellent stability for orbital wall reconstruction at the infraorbital rim, and produced satisfactory ophthalmologic functional results with no intraoperative or postoperative complications. This material may be an optimal bioactive, osteoconductive, and bioresorbable bone alternative for orbital wall reconstruction with fewer complications in patients with orbital fractures.

Applicability of an Unsintered Hydroxyapatite Particles/Poly-L-Lactide Composite Sheet with Tack Fixation for Orbital Fracture Reconstruction