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The leunca plant (Solanum nigrum L.) is a plant consumed by Indonesians. Leunca plant leaves are widely used for herbal medicines. The research was conducted to determine the compound content and antioxidant activity of leunca (Solanum nigrum L.) leaf extract. The method used in this research is the phytochemical test and the DPPH method. Samples of fresh leunca (Solanum nigrum L.) leaves were picked and collected. Samples were stored in a cool place and then dried in an aerated manner in open air protected from sunlight for 7 days. Fresh leaves and dried leaves are brownish then chopped until smooth and then blended until smooth. The extract obtained was followed by a phytochemical test with a color reaction. The antioxidant activity of leunca leaf extract (Solanum nigrum L.) was tested using the DPPH (1-1-diphenyl-2-pikrilhidrazil) method, with 5 different concentrations, namely 25, 50, Metamorfosa:Journal of Biological Sciences 8(1): 28-34 (Maret 2021) eISSN: 2655-8122 29 75, 125 and 150 ppm of dried leunca leaves and leaf extract. Fresh leunca 200, 400, 600, 800, and 1,000 ppm and consisted of 4 replications, analyzed by T test. The positive leunca leaf extract contained alkaloids, steroids / triterpenoids, flavonoids, phenols and tannins. The results showed that the dried leunca leaf extract and the fresh leunca leaf extract had different antioxidant activities. Dried leunca leaf extract is classified as a strong antioxidant because it has an the IC50 value of 95.12 ppm and fresh leunca leaf extract is classified as a weak antioxidant with an IC50 value of 243.66 ppm. IC50 is classified as a strong if it has a value of 50-100 ppm, 100-150 ppm is classified as moderate, 150-200 ppm is weak and 150-200 ppm is classified as very weak.

Uji Antioksidan Ekstrak Daun Tanaman Leunca (Solanum nigrum L.)