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This study aims to prove that the extract of Moringa leaf can improve renal histological structure of diabetic Wistar rats. Wistar rats were divided into six groups, so that each group has four replications. The K1 group as the positive control was not given the extract, K2 group was administered the extract dose of 100 mg/kg, K3 group was administered the extract dose 200 mg/kg, K4 group was administered the extract dose 300 mg/kg, K5 group was administered the extract dose 400 mg/kg, and K6 group was given the extract dose 500 mg/kg, which was carried out for five weeks. Rats were then sacrificed and the kidneys were taken for the histopathology preparations with Hematoxylin-Eosin staining (HE). The results showed fatty degeneration and necrosis of the kidneys. Kruskal Wallis test results of all treatments showed p = 0.001 both in fatty degeneration and necrosis (p <0.05).

HISTOPATHOLOGICAL KIDNEY OVERVIEW OF EXPERIMENTAL DIABETES MELLITUS WISTAR RATS GIVEN ETHANOL EXTRACT OF MORINGA LEAF