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Background. Brain metastases represent the most serious complication in lung cancer, and synchronous multiple brain metastases from lung cancer have been considered to indicate an unfavorable prognosis. Case. A 60-year-old man was seen for evaluation of a severe headache. A CT scan of the brain demonstrated multiple tumors in the right parietooccipital and frontotemporal regions. A chest X-ray revealed an abnormal shadow in the apex of the right lung, and a CT scan revealed a 1.4•~1.2cm mass with spiculation in the right S1 region. The patient underwent right occipitotemporal and frontal craniotomy, and two masses were completely removed. Then, he received wholebrain radiation therapy. Six weeks later, he underwent right upper lobectomy. Histologically, the lesions of both the brain and the lung were squamous cell carcinomas, and brain tumors proved to be metastatic tumors from the lung cancer. He has been well with no evidence of recurrence for 7 years. Conclusion. Synchronous oneset of multiple brain metastasis from lung cancer does not necessarily represent an unfavorable prognosis, and combined resection with radiation therapy can provide long-term survival in selected patients. (JJLC. 2002; 42: 45-49) KEY WORDS-Lung cancer, Synchronous multiple brain metastasis, Combined resection, Long-term survival 1 三 重 大学 医学 部 胸部 外 科. 別 刷 請 求先:藤 永 一 弥,三 重 大 学 医学 部 胸 部外 科,〒514-8507 三 重 県 津 市 江 戸 橋2-714 (e-mail: kazu9911@clin.medic.mie-u.ac. jp). 1 Thoracic and Cardiovascular Surgery , Mie University School of Medicine, Japan. Reprints: Kazuya Fujinaga, Department of Thoracic and Cardiovascular Surgery, Mie University School of Medicine, 2-174 Edobashi, Tsu-shi, Mie 514-8507, Japan (e-mail: kazu9911@clin. medic.mie-u.ac.jp). Received October 24, 2001; accepted January 7, 2002. (c) 2002 The Japan Lung Cancer Society Japanese Journal of Lung Cancer-Vol 42, No 1, Feb 20, 2002-www.haigan.gr.jp 45 Long-term Survival Case of Lung Cancer With Synchronous Brain Metastases-Fujinaga et al

A Long-term Survival Case After Removal of Synchronous, Multiple, Brain Metastases Followed by Resection of Lung Cancer.