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collagen (type 1V and VII), laminin, and fibronectin, among other substances. In 1979, Kamino and colleagues described dull pink globules in the epidermis of 65% of junctional, 75% of compound, and 25% of intradermal types of Spitz nevi (the nevi of large spindle and/or epithelioid cells). These globules were PAS-positive, diastaseresistant, and positive on trichrome staining. Similar eosinophilic globules were noted in the epidermis in only 2% of malignant melanomas and 0.9% of ordinary melanocytic nevi. The globules in malignant melanomas and ordinary melanocytic nevi were negative with PAS and trichrome staining. Kamino and colleagues concluded that PASand trichrome-positive eosinophilic globules in the epidermis can aid in the histological differentiation of Spitz nevus from malignant melanoma. In a latter publication (6), Dr. Kamino studied 9 cases of Spitz nevi of compound type, which had large homogeneous eosinophilic globules at the dermoepidermal junction. All 9 cases were positive Abstract

Hideko Kamino and the eponym linked to her name / Hideko Kamino i eponim vezan za njeno ime