English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Evaluation of potential antiinflammatory activity of copper (ii) and zinc(ii) benzene-1, 4-diylbis(oxyacetates), free benzene-1, 4-diylbis(oxyacetic)acid and their mixtures in rats Using rat paw dextran- and/or carageenan-induced edemas, the antiinflammatory activity of copper(II) and zinc(II) benzene-1,4-diylbis(oxyacetates) (compexes 1c and 1z) and free benzen-1,4-diylbis(oxyacetic)acid (1a) and their equimolar mixtures (1cz, 1ac and 12az) were evaluated plethysmometrically. All the tested compounds were administered intraperitoneally in the single dose 50μmol/kg of body weight (calculated for the carboxylate fragment) 30 minutes before injecting the irritant. The antiphlogistic activity of the compounds (expressed as a mean edema reduction) was found as: 1a 27.6 % / -23,0 % < 1c 44.2 % / 34.7 < 1z 69.2 % / 30.3 % < 1cz 59.7 % / 67.0 % < 1ac 53.1 % / 77.6 % < 1az 83.8 % / 85.5 %. The relationships between the coordination-chemical properties and the biological effects on the corresponding compounds are discussed. Hodnotenie potenciálnej protizápalovej aktivity kuprum(ii) a zinkum(ii) benzen-1, 4-diylbis(oxyacetatu), voľnej benzen-1, 4 diylbis(oxyoctovej kyseliny) a ich zmesí u potkanov Protizápalová aktivita kuprum(II) a zinkum(II) benzén-1,4-diylbis(oxyacetátu) (komplexy 1c a 1z) a voľná benzén-1,4-diylbi-(octová kyselina) (kyselina 1a) a ich ekvimólové zmesi (1cz, 1 ac a 1az) bola hodnotená pletyzmometricky na dextranovom, resp. karagenínovom edéme na potkanoch. Všetky testované látky boli podané i.p. v jednorázovej dávke 50μmol/kg telesnej hmotnosti zvieraťa (počítané na karboxylátový fragment) 30 min. pred injikovaním iritanta. Priemerná antiflogistická aktivita látok (vyjadrená ako miera redukcie edému) bola zistená v tomto poradí: 1a 27.6 % / -23,0 % < 1c 44.2 % / 34.7 < 1z 69.2 % / 30.3 % < 1cz 59.7 % / 67.0 % < 1ac 53.1 % / 77.6 % < 1az 83.8 % / 85.5 %. Diskutujeme vzťahy medzi koordinačno-chemickými vlastnosťami a biologickým účinkom príslušných komplexov

acta facultatis pharmaceuticae universitatis comenianae

Evaluation of potential antiinflammatory activity of copper (ii) and zinc(ii) benzene-1, 4-diylbis(oxyacetates), free benzene-1, 4-diylbis(oxyacetic)acid and their mixtures in rats