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The Effects of a Yoga Intervention on Balance, Speed and Endurance of Walking, Fatigue and Quality of Life in People with Multiple Sclerosis Multiple sclerosis (MS) is a disease of the central nervous system that results in many symptoms including mobility limitation, fatigue and redacted quality of life. The purpose of this study was to determine the effect of a yoga intervention on balance, speed and endurance of walking, fatigue and quality of life in MS patients. 21women with MS (34.38±5,68) with Expanded Disability Status Scale scores 1.0 to 4.0, have been randomly assigned to a yoga group or control group. Yoga group subjects participated in a thrice weekly 60-70 minute sessions of Hatha yoga intervention for 8-weeks. Balance, speed and endurance of walking, fatigue and quality of life were measured by Berg Balance scores; 10-m time and 2-minute distance walking, Fatigue Severity Scale (FFS) and Multiple Sclerosis Quality of Life-54 questionnaire (MSQOL-54) respectively. Comparison of results of pre and post intervention revealed significant improvement on balance score, walking endurance, FFS and some of MSQOL-54 scale scores in the yoga group (p≤0.05 respectively). There were no clear changes in10-m times (p= 0.132), related to yoga group. No changes were observed for control group. These results suggest that yoga intervention can be beneficial for patients with MS