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Hydroxyproline Levels in Young Adults Undergoing Muscular Stretching and Neural Mobilization This study aimed to assess the acute effect of stretching and neural mobilization on urinary hydroxyproline (HP) levels in young adults. The sample, composed of physical therapy students from Teresina (PI), was divided into three groups: a neural mobilization group (NMG; n=15; age=22±3 years; BMI=24.75±3.09); a static stretching group (SSG; n=15; age=23±4 years; BMI: 25±4.33) and a control group (CG; n=15; age: 24±4 years; BMI: 23.91±3.09). The NMG underwent neural mobilization of the sciatic nerve while engaged in hip flexion with knee extension in a direct, oscillatory and strenuous manner for 60 seconds. The SSG performed passive static stretching, which consisted of the maintenance of a high amplitude posture, without exceeding the limits of the movement, for a period of tension ranging from four to six seconds. Urinary HP was evaluated at the baseline and 24 hours after the intervention using the colorimetric method. Repeated measures ANOVA showed significant intragroup increases in the NMG (Δ7.38 mg/24h; p=0.0001) and the SSG (Δ=3.47 mg/24h; p=0.002) and inter-group increases in the NMG (Δ%=118.89%) when compared to the SSG (Δ%=60.32%; p=0.006) and the CG (Δ%=-0.91%; p=0.0001). These results indicate that the NMG worked with tension beyond the ordinary amplitude arches of articular movement, thus causing a restructuring of collagen. Nivoi Hidroksiprolina Kod Mladih Pacijenata na Terapiji Mišićnog Istezanja i Neuralne Mobilizacije Cilj studije bio je da se proceni akutni efekat istezanja i neuralne mobilizacije na nivoe hidroksiprolina (HP) u urinu mlađih odraslih osoba. Uzorak, koji su činili studenti fizikalne terapije iz Terezine, podeljen je u tri grupe: grupa za neuralnu mobilizaciju (NMG; n=15; starost: 22±3 godine, indeks telesne mase (BMI): 24,75±3,09); grupa za statičko istezanje (SSG; n=15; starost: 23±4 godine; BMI: 23,91±3,09). NMG podvrgnuta je neuralnoj mobilizaciji išijatikusa tokom fleksije kuka uz ekstenziju kolena uz direktan, oscilatoran i naporan pokret tokom 60 sekundi. SSG izvodila je pasivno statičko istezanje, sastavljeno od održavanja položaja s velikom amplitudom, ne prelazeći granice pokreta, za period naprezanja od četiri do šest sekundi. HP u urinu određen je na početku i 24 časa posle intervencije pomoću kolorime-trijske metode. Ponovljena merenja pomoću ANOVA pokazala su značajne poraste u NMG (d=7,38 mg/24h; p=0,0001) i SSG (Δ;=3,47 mg/24h; p=0,002) i poraste u NMG (Δ%=118,89%) u poređenju sa SSG (Δ%=118,89%) u poređenju sa SSG (Δ%=60,32%; p=0,006) i CG (Δ%=-0,91%; p=0,0001). Rezultati ukazuju na to da je NMG radila s tenzijom izvan uobičajenih lukova amplitude artikularnog pokreta, što je izazvalo restrukturaciju kolagena.