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Background:  131 I-metaiodobenzylguanidine (mIBG) offers an effectively targeted radionuclide therapy in pediatric patients. According to radiation protection authority in our country, the patient treated with high-dose (&gt;1100 MBq) radioiodine is recommended to stay in the hospital. Hence, this study intends to measure the radiation exposure in nonlead-lined treatment room installing with portable lead shields located in general pediatric ward and surrounding areas. In addition, this study also aims to measure the radiation exposure to the family caregiver in pediatric patients received high dose  131 I-mIBG. Methods: Environmental OSL (optically stimulated luminescence) monitoring devices (InLight®, Al 2 O 3 :C) were prepared and calibrated by Thailand Institute of Nuclear Technology (TINT). Twenty-five set of OSLs were placed in and surrounded the treatment room. Dose to family caregiver was recorded by digital semiconductor dosimeter (ALOKA PDM-112) also calibrated by TINT. The measurement was carried for four pediatric patients treated with  131 IMIBG (activity 3700 – 5500 MBq). Results: The ambient doses equivalent and the dose rate were analyzed, the limit of 10 and 0.5 μSv/h are accepted for radiation worker and member of the public, respectively. The dose rate around the patient bed and toilet were high as expected. Dose rates at the wall of adjacent room and corridor were slightly greater than the public limit (range 1.82 to 4.48 μSv/h). Remarkably, the dose rates at caregiver chair (outside the shielding) were exceeded the limits (30.57 ± 5.69 μSv/h). Consequently, this was correlated with high personal dose equivalent to family caregivers which listed as 175, 1632, 6760 and 7433 μSv for the patient age of 15, 5, 1 and 1 year respectively. Conclusion: These radiation monitoring data provided the important information to manage radiation protection and aware of radiation exposure when using non-lead-lined treatment room in general pediatric ward.

Radiation monitoring of non-lead-lined treatment room in general pediatric ward and adjacent areas for high dose 131Iodine-mIBG

Radiation monitoring of non-lead-lined treatment room in general pediatric ward and adjacent areas for high dose ¹³¹Iodine-mIBG