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Objective This study evaluated the effects of combined ethanol extract of  Funtumia africana  and  Abutilon mauritianum  leaves (FAAM) on the liver function indices of benign prostatic hyperplasia (BPH) induced rats. Materials and Methods The study used 30 rats divided into 5 groups, comprising normal control, BPH control, standard control, and BPH induced rats treated with 200 and 600 mg/kg/day of FAAM respectively. Results The BPH induction caused significant ( p  0.05) reduced AST, and alanine transaminase (ALT) activities relative to the BPH control. The BPH-induced rats treated with 600 mg/kg/day of FAAM had significantly ( p &lt;0.05) reduced ALP activities relative to the BPH control. Treatment with FAAM caused significant ( p &lt;0.05) increases in the total protein, albumin, globulin concentrations and significant ( p &lt;0.05) reductions in the total bilirubin and direct bilirubin concentrations relative to the BPH control. BPH had no observable adverse effects on the liver histomorphology of the rats. Conclusion The findings of this study indicated that BPH impairs liver functions and treatment of BPH with combined ethanol extract of  F. africana  and  A. mauritianum  leaves restore normal liver functions in rats with BPH.

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Effects of combined ethanol extract of <i>Funtumia africana</i> and <i>Abutilon mauritianum</i> leaves (FAAM) on liver function indices of benign prostatic hyperplasia (BPH) induced rats

Effects of combined ethanol extract of Funtumia africana and Abutilon mauritianum leaves (FAAM) on liver function indices of benign prostatic hyperplasia (BPH) induced rats