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The fungi of the genus  Ophiocordyceps sinensis  (Berk.) belong to entomopathogenic fungi.  Ophiocordyceps sinensis  has been used as a tonic and medicinal product in China for more than 2,000 years. A number of scientific papers have described the clinical use of this parasitic fungus with subsequent biological and pharmacological effects. The various chemical compounds identified in these fungi are responsible for a wide range of biological activity: cordycepin, cordycepic acid, D-mannitol, polysaccharides, nucleotides, proteins, amino acids, and unsaturated fatty acids. Our research focused on the determinations of the biologically active chemical compounds in extracts from cultivated  Ophiocordyceps  fungi using UV/VIS (Ultraviolet/Visible) spectrophotometry and NMR (Nuclear Magnetic Resonance) spectroscopy. The testing of antimicrobial activity of extracts against the collection strains of  Escherichia coli  and  Staphylococcus aureus  demonstrated that the percentage of RIZD (relative inhibition zone diameter) ranged from 83 % to 166 %. The increased antimicrobial activity against  E. coli  was observed in comparison with that against  S. aureus.

Medicinal Mushrooms Ophiocordyceps Sinensis and Paecilomyces Hepiali