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Objective To explore the application of plan–do–check–action (PDCA) cycle in the management of the naked medicine dispensing about the automatic package and to analyze the practice improved in the quality of naked medicine dispensing medicine management. Methods The PDCA theory was used to analyze the data, to find out the causes of the problem, and to formulate the corresponding countermeasures to intervene. The data of the naked medicine/adverse drug events satisfaction degree of the inpatients in 18 inpatient departments given for the adoption of PDCA cycle in January 2017 were set as the observation group. The number of the naked medicine/adverse drug events satisfaction degree of patients in 18 inpatient departments before adoption of PDCA cycle in December 2016 was set as the control group. The number of the naked medicine/adverse drug events satisfaction degree of patients in 18 inpatient departments before and after adoption of PDCA cycle was observed and analyzed. Results The number of the naked medicine/adverse drug events after implementing the method of PDCA cycle management rate was significantly lower than before the implementation method of PDCA cycle management, and the difference had statistical significance ( P  &lt; 0.05). The satisfaction degree of the inpatients after implementing the method of PDCA cycle management rate was significantly higher than that before the implementation method of PDCA cycle management, and the difference had statistical significance ( P  &lt; 0.05). Conclusion Application of PDCA cycle in the management of the naked medicine dispensing about the automatic package can help to reduce the adverse drug events, to improve the safety of drug treatment, and to increase the patients’ satisfaction degree.

Analysis of the application and practice of PDCA cycle in management of the naked medicine dispensing—the quality and safety of the drug