English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Digenetic trematode infections including schistosomiasis and fascioliasis have highly neglected statuses but are a menace to people in the poorest countries of the tropics, causing high morbidity and mortality in humans as well as great global losses in livestock production. This has neccesitated the widespread search for better control options for the snail vectors of these diseases. Hence, a novel drug - curcumin and nisin poly lactic acid (PLA) entrapped nanoparticles (CurNisNp) was screened for molluscicidal activity against the adults (&gt; 2 months old) of  Biomphalaria pfeifferi, Bulinus globosus  and  Lymnaea natalensis  vector snails. Mortality was determined after 96-h of exposure at varying concentrations. The snails of the species  L. natalensis  were found to be the most susceptible to the molluscicide (LC 50  323.6 ppm). This finding further supports the desirability of curcumin-nisin polylactic acid (PLA) nanoparticles as a molluscicide and therefore shows that it could be a good alternative to conventional molluscicides with prospects in the selective control of fascioliasis. However, more optimization of the drug could ensure a greater molluscicidal potency.

advanced research in life sciences

Molluscicidal Activities of Curcumin-Nisin Polylactic Acid Nanoparticle (PLA) on Adult Snail Intermediate Hosts of <i>Schistosomes</i> and <i>Fasciola</i> spp.

Molluscicidal Activities of Curcumin-Nisin Polylactic Acid Nanoparticle (PLA) on Adult Snail Intermediate Hosts of Schistosomes and Fasciola spp.