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Sho-seiryu-to, one of the traditional Chinese medicines was used in tracheostomy patients in an attempt to eradicate methicillin-resistant Staphylococcus aureus (MRSA). Sho-seiryu-to was administered to 10 patients and eliminated MRSA in 6 of these. Another study was performed to determine the anti-MRSA activity of kampo medicines. The antibacterial activity of 4 kampo medicines (Sho-seiryu-to, Sho-saiko-to, Juzen-taiho-to and Ninjin-yoei-to) was measured. Sho-seiryu-to had an anti-MRSA effect, but the other 3 kampo meds. had no effect. Investigation of the anti-MRSA activity due to the different components of Sho-seiryu-to was performed by the dilution method. Ephedra herb was effective, glucyrrhiza root, cinnamon bark, schizandra fruit, peony root and dried ginger rhizome were slightly effective; while pinellia tuber and asiasarum root were not effective.

nihon kikan shokudouka gakkai kaihou/nihon kikan shokudōka gakkai kaihō

Sho-seiryu-to Therapy for Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in Tracheostomy Patients and the Anti-MRSA Activity of Kampo Medicines.