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23 Na-MRI provides information on Na + content, and its application in the medical field has been highly anticipated. However, for existing clinical 1 H-MRI systems, its implementation requires an additional broadband RF transmitter, dedicated transceivers, and RF coils for Na + imaging. However, a standard medical MRI system cannot often be modified to perform 23 Na imaging. We have developed an add-on crossband RF repeater system that enables 23 Na-MRI simply by inserting it into the magnet bore of an existing 1 H MRI. The three axis gradient fields controlled by the 1 H-MRI system were directly used for 23 Na imaging without any deformation. A crossband repeater is a common technique used for amateur radio. This concept was proven by a saline solution phantom and in vivo mouse experiments. This add-on RF platform is applicable to medical 1 H MRI systems and can enhance the application of 23 Na-MRI in clinical usage.

magnetic resonance in medical sciences

Development of an Add-on &lt;sup&gt;23&lt;/sup&gt;Na-MRI Radiofrequency Platform for a &lt;sup&gt;1&lt;/sup&gt;H-MRI System Using a Crossband Repeater: Proof-of-concept