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Although there is no lymphatic system in the central nervous system (CNS), there seems to be a mechanism to remove macro molecules from the brain. Cerebrospinal fluid (CSF) and interstitial fluid (ISF) are thought to be parts of this pathway, but the details are not known. In this study, MR signal of the extracellular water was decomposed into components with distinct T 2 's, to obtain some information about distribution of waste material in the brain.

magnetic resonance in medical sciences

The Spatial Distribution of Water Components with Similar T&lt;sub&gt;2&lt;/sub&gt; May Provide Insight into Pathways for Large Molecule Transportation in the Brain