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Magnetic resonance (MR) imaging offers the highest sensitivity for detecting bone necrosis. We evaluated osteonecrosis in rabbit models by calculating the percentage of fat to (fat + water) [F/(F+W)] on MR spectroscopy (MRS) and compared MR spectroscopy and imaging findings with corresponding histological results.

Time Course of Osteonecrosis in Rabbit Articular Intercalated Bone: Line Scan Spectroscopic Imaging and Correlation with Histology