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Diabetes Mellitus (DM) is a state of chronically hyperglycemia, which is caused by impaired insulin secretion and function. The alteration in coagulation system in DM patients served as the basic etiology of macro and micro vascular complication. Platelets are one of the factors that have a role in the coagulation system and undergo pathological changes in DM patients. Mean Platelet Volume (MPV) is an indicator of platelet function and activation. Larger platelets have more dense and more reactive pro coagulant granules. The aim of this study was to know whether there were differences in MPV between DM patients compared to medical check-up participants at the Dr. Hasan Sadikin Hospital, Bandung.. The research used analytical descriptive, retrospective data. The inclusion criteria of this research was DM patients and medical check up participants whose serum fasting glucose and two (2) hours post prandial serum glucose were within the normal range. The data were taken from medical records of DM patients and medical check up participants. The data were further analyzed with SPSS ver. 15 program using unpaired T-test. In this study, no significant difference between DM patients and medical check up participants (p>0.05) was found. It can be concluded that Mean Platelet Volume if used as single, can not predict vascular complication in DM patients.

RERATA VOLUME TROMBOSIT DI DIABETES MELITUS (Mean Platelet Volume in Diabetes Mellitus)