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The current study was achieved  to investigate for some of biochemical parameters associated with pollution of sheep with petroleum derivatives and it's effects on some parameters of oxidative stress and antioxidant. The blood samples were collected from 70 sheep and divided  into  two groups, the first group included 15 from other city and very far from center of pollution ( about 200 Klm)  which consider as a control group, while  the second group included 55 sheep near the center of pollution ( about 3 Klm)  which represent affection group. The results showed that the affection group cause significant  increase in oxidative stress parameters  (Malondialdehyde , peroxynitrate radical ) (P≤0.05). and we see from this study significant  decrease in antioxidant parameters  (Glutathione, glutathione peroxidase enzyme , superoxide dismutase enzyme ) in the affection group. We can concludes from this study that the Effect of petroleum derivatives impact adversely on antioxidants accompanied by an increase in the level Malondialdehyde and peroxynitrate radical which consider as indicators for oxidative stress that is a companion Effect of petroleum derivatives.

Effect of petroleum derivatives on some antioxidant and oxidative stress parameters in sheep in Khanaqeen city