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The present study was undertaken to assess and compare the serum biochemical parameters of buffalos and cows brucellosis with negative ones .A total of ninety three blood samples were collected randomly from different age and flocks of non vaccinated local buffalos and cows. Rose Bengal Plate Test was depended for screening the collected blood samples in addition to measure serum biochemical parameters included total protein, albumin, cholesterol, triglyceride, urea, creatinine, aspartate transaminase (AST) and alanine transaminase ( ALT). It was observed that 12 (12.9%) samples positive for Brucella spp. The results of biochemical parameters shown that ALT, AST and total protein were increased significantly ( p<0.05) in buffalo positive for brucellosis than those of negative results .The values of the albumin, cholesterol, triglyceride, urea and creatinine did not show significant variation between the Brucella positive and negative buffalo. The values of serum cholesterol, triglyceride and creatinine concentrations for Brucella positive cows were declined significantly ( p<0.05) when compared to negative ones . The value of AST was elevated significantly ( p<0.05) in Brucella positive cows. It was noticed that there were no significant differences between positive and negative cows considering total protein, albumin, urea and ALT. cows .These changes in biochemical parameters of the blood indicate that brucellosis causes deteriorative effects on health of buffalo and cows infected with Brucella.

Biochemical parameter evaluation Buffalos and Cows with brucellosis in Missan Province