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Objective : To determine the antibacterial activity of aqueous grape extracts (Vitis vinifera) obtained from the skin, seed and pulp, on Streptococcus mutans (ATCC 35668, Ecuador), using 0.12% chlorhexidine as a positive control and distilled water as a negative control. Materials and methods : Aqueous extracts were obtained from the pulp, seeds and grape skin of the northern region of Ecuador, at a concentration of 40, 70 and 100%, which were impregnated 20 ml each in paper filter discs. and placed in Petri dishes with strains of Streptococcus mutans inoculated on blood agar, disks impregnated in 0.12% chlorhexidine and distilled water were used as control; the antimicrobial activity was evaluated considering the inhibition zones obtained at 24 and 48 hours of incubation. Results : The evaluation times 24 and 48 were different (p = 0.00) showing a greater inhibitory effect at 48 hours, where the 100% grape seed extract presented antimicrobial activity similar to 0.12% chlorhexidine, and the 70% concentration of the same extract reduced inhibition. However, peel and pulp extracts in their different concentration did not present halos of inhibition against Streptococcus mutans. Conclusions : The aqueous extract of 100% grape seeds showed antimicrobial activity similar to 0.12% chlorhexidine against Streptococcus mutans.

Efecto antimicrobiano de extractos acuosos de la cáscara, pulpa y semilla de uva (vitis vinifera) sobre streptococcus mutans, estudio in vitro