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Seasonal variations have an influence on the availability of secondary metabolites of plants, which impacts their therapeutic efficacy. For some plants, the bioavailability of secondary metabolites, and thus the harvest period, is better in the spring, while for others it is summer. Celtis australis (Cannabaceae), a deciduous tree, is used in the treatment of various diseases in many traditional systems around the world. In the present work, seasonal influence on total polyphenols, flavonoids and condensed tannins contents as well as on the antioxidant potential of leaves hydromethanolic extract from Celtis australis have been evaluated. Plant leaves were harvested during spring and summer which are its flowering and fruiting seasons respectively. The total phenols, flavonoids and condensed tannins contents were quantified by spectrophotometry using Gallic acid, Quercetin and Catechin as standards respectively. The antioxidant potential of the plant extracts was evaluated using three complementary methods: DPPH radical scavenging activity, conjugated dienes and TBARS inhibition during linoleic acid peroxidation. Our results showed that the levels of all quantified compounds increased significantly during the growing season until midsummer and this increase is positively correlated with the antioxidant Seasonal ... Ahmed EL ABBOUYI. 344 IJGHC, June 2019 –August 2019; Sec. B; Vol.8, No.3, 343-352. DOI: 10.24214/IJGHC/HC/8/3/34352. potential of the plant extract. It can be concluded that leaves harvesting should occur in the middle of the summer to obtain a better medicinal efficacy of the plant.

Seasonal variations in phenolics and antioxidant properties of leaves extract from Celtis australis