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--Introduction: The global population is aging, and the number of elderly people continues to increase worldwide. The increase in the elderly population is followed by an increase in problems due to degenerative processes that have an impact on the quality of life of the elderly. Several factors that affect the quality of life of the elderly include physical activity, functional abilities, and depression. Methodology: The study design was cross-sectional. Based on the quota sampling in East Jakarta, 180 elderly were selected as the sample. WHOQOL-BREF was used to measured quality of life of independent variables. GPAQ, IADL-Barthel Index, GDS were used to measure dependent variables of physical activity, functional ability and depression, respectively. The Data collection method was an interview using a questionnaire. Data analysis includes univariate and bivariate analysis using Chi-Square test and multivariate analysis using Logistic Statistics test using Enter method. Results: Most of the elderly have a good quality of life (77.2%). There was a significant corellation between physical activity, functional ability, depression and the quality of life of the elderly. The most important factor was physical activity and the P values and OR were 0.014 and OR 3.409, respectively after being controlled by the variables of functional ability and depression. Conclusion: The finding indicated physical activity was the key factor of quality of life. In order to support elderly to exercise regularly and safely, cooperation between local governments, communities, and families is needed to develop interesting exercise/leisure sport programs and provide support facilities for the elderly. Keywords— quality of life, physical activity, functional ability, depression, elderly

Is Physical Activity, Functional Ability, and Depression Related to The Elderly Quality of Life in East Jakarta?