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Indonesian civil aviators have a risk of experiencing stress due to fatigue factor with high-frequency intersection routes between islands of Indonesia. Salivary α-amylase is an enzyme that can be used as a stress biomarker. This study was aimed to analyse the differences of salivary α-amylase levels in Indonesian civil aviators with and without fatigues stress experience. Methods: This research was cross-sectional, comparing the level of fatigue as the cause of stress for Indonesian civil aviators with the Fatigue Severity Scale (FSS) measurement method. The level of the salivary α-amylase enzyme was analysed using the ELISA method in two groups: Indonesian civil aviators with more than 6624 flight hours and performed sector flights (24 subjects); Indonesian civil aviators with less than 6624 flight hours and did not perform sector flights (16 subjects). All data then analysed with comparative bivariate data analysis. Results: The group of Indonesian civil aviators with more than 6624 flight hours and performed sector flight showed an α-amylase enzyme value of 0.899; while the group of Indonesian civil aviators with less than 6624 flight hours and did not perform sector flights showed an α-amylase enzyme value of 0.689. There was a significant difference p=0.006 (p < 0.05) between the two groups of pilots. Conclusion: Indonesian civil aviators with fatigues stress experience of increases the α-amylase enzyme value compared to Indonesian civil pilots without fatigues stress experience.

padjadjaran journal of dental researchers and students

&lt;p&gt;Perbedaan kadar enzim α-amylase saliva pada penerbang sipil Indonesia yang mengalami stress dan tidak stress karena faktor kelelahan&lt;/p&gt;&lt;p&gt;Differences in the salivary α-amylase levels in Indonesian civil aviators with and without fatigues stress experience&lt;/p&gt;