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The aim of the study was to investigate the presence of the five most aggressive periopathogens in patients with generalized aggressive severe periodontitis before treatment. A total of 86 systemic healthy people, from 11 to 35 years old, were included in the study. The real time Polymerase Chain Reaction (PCR) method was used for detection of periopathogens. The qualitative and quantitative content of Porphyromonas gingivalis, Tan-nerella forsythensis and Treponema denticola of patients with aggressive periodontitis was significantly more than patients with chronic periodontitis.

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