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BULLETIN OF RSMU 4, 2019 VESTNIKRGMU.RU | | According to the WHO, 11 to 13% of the world's population suffer from osteoarthritis (OA). OA affects both the elderly, for whom it is one of the main causes of disability, and the working age people [1–4]. Peculiar to the disease are chronic pain, destruction and loss of articular cartilage, remodeling of subchondral bone, formation of osteophytes, inflammation of the synovial membrane of varying degree, involvement of both intraarticular and paraarticular structures in the pathological process [5]. For a long time, it was the articular cartilage that was believed to be the driver of OA development. However, in the last decade the role of the subchondral bone (SB) has been attracting attention both from the point of view of etiopathogenesis and Lychagin AV, Garkavi AV, Islaieh OI , Katunyan PI, Bobrov DS, Yavlieva RH, Tselisheva EYu EFFECTIVENESS OF INTRAOSSEOUS INFILTRATION OF AUTOLOGOUS PLATELET-RICH PLASMA IN THE AREA OF THE BONE MARROW EDEMA IN OSTEOARTHRITIS OF THE KNEE JOINT

Effectiveness of intraosseous infiltration of autologous platelet-rich plasma in the area of the bone marrow edema in osteoarthritis of the knee joint