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The study involved 117 human fetuses aged 5 to 10 months of prenatal development (85,0-500,0 mm parieto-calcaneal length) of both sexes by means of complex of morphological methods (anthropometry, morphometrics, computed tomography, three-dimensional computer constructing, statistical analysis). Statistical analysis of morphometric parameters of nasal region structures of both sexes fetuses during fetal period of human prenatal ontogenesis allowed to clarify and determine the features of sex and age anatomy, elucidate mathematical regularities of morphometric parameters changes in investigated structures, which can be a morphologic basis for developing diagnostic algorithms and solving issues of human fetus maturity degree. Periods of uneven growth of nasal region morphometric parameters are 5 and 8 months of fetal development during which is its size accelerated growth in both fetus sexes; also 7 month, when its growth is decelerated. Mathematical analysis of morphometric changes features of the nasal aperture and nasal cavity allowed to withdraw logarithmic functions, which reflect patterns of this structures dynamic changes: width of nasal cavity (male) y=6,6219*exp(0,1178*x); width of nasal cavity (female) y= 6,323*exp(0,128*x); length of nasal cavity (male) y=11,9296*exp(0,1076*x); length of nasal cavity (female) y=11,6504*exp(0,0992*x); width of nasal aperture (male) y=5,8844*exp(0,1116*x); width of nasal aperture (female) y=5,8259*exp(0,0914*x); height of nasal aperture (male) y= 6,9016*exp(0,1418*x); height of nasal aperture (female) y=7,0358*exp(0,1004*x).

Mathematical modeling of regularities of morphological parameters age dynamics of the nasal region in human fetuses