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Pandemic leads to major mortality and morbidity. Many pandemics occur over the centuries, but the mother of all pandemic was "Spanish Flu" and nowadays we are facing another huge uncontrollable "Covid 19" pandemic of the current century. The purpose of this comparative review is to help and provide guidance for frontline medical staff in dealing with this current outbreak to differentiate and seek information with the previous pandemic and get knowledgeable guidance for future dealings of COVID-19. Peer-reviewed literature on the outbreaks of infectious disease has steadily increased in recent years, but the major pandemics should be compared to find out the similarities and differences. To do so, we provide step by step contents of both diseases.

A Narration: 20th v/s 21st Century: Pandemic v/s Another Pandemic: Virus v/s Another Virus (Spanish Flu V/S COVID-19)