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Objective: to conduct contrastive analysis of treatment effect of peritoneoscope plus intrathoracic anastomosis for esophageal cancer resection (Ivor-Lewis surgery) and peritoneoscope plus neck anastomosis for esophageal cancer resection (McKeown surgery) on Stage T1-3N0M0 middle-lower section esophageal cancer. Method: the research period is from January 1, 2015 to December 31, 2017. The research objects include 100 patients with Stage T1-3N0M0 middle-lower section esophageal cancer. They were classified into Ivor-Lewis group (50 cases, treatment with Ivor-Lewis surgery) and McKeown group (50 cases, treatment with McKeown surgery) with random number table. Conventional surgical indexes of patients, surgical index, QLQ-OES18 and postoperative complications were compared and analyzed. Results: the surgery duration, intraoperative blood loss volume, lymph node dissection quantity, and average hospital stay had no significant differences in both groups, and there was no statistical significance (P>0.05). (2) QLQ-C30 3.0 score and QLQ-OES18 score of Ivor-Lewis group were higher than that of McKeown group, and the difference had statistical significance (P<0.05). (3) The total occurrence rate of complications in Ivor-Lewis group was higher than that of McKeown group, and the difference was significant and had statistical significance (P<0.05). Conclusion: for treatment of Stage T1-3N0M0 middle-lower section esophageal cancer, Ivor-Lewis surgery and McKeown surgery have little difference in surgical indexes, but complication occurrence rate of Ivor-Lewis group is low, and the living quality is high. Thus, it can be used as the optimal method to treat Stage T1-3N0M0 middle-lower section esophageal cancer. Surgical excision is often applied for early treatment of esophagus cancer. Although this method has certain therapeutic effect, postoperative recovery of patients is slow and there are multiple complications. Meanwhile, postoperative living quality of patients is low. The development of minimally invasive technology provides more methods for esophagus cancer treatment. Compared with surgical excision, obvious minimally invasive advantage exists. In recent years, some 2018 7th International Conference on Medical Engineering and Biotechnology (MEDEB 2018) Published by CSP © 2018 the Authors 204 literatures indicate that Ivor-Lewis surgery is more preponderant than McKeown surgery in treatment of middle-lower section esophageal cancer, which is mainly reflected in complication occurrence aspect. Considering the above research belongs to retrospective analysis report, prospective randomized controlled study will be applied in this paper to discuss the application of Ivor-Lewis surgery and McKeown surgery in Stage T1-3N0M0 middle-lower section esophageal cancer. The detailed analysis is as follows: 1. Clinical Data and Method

Prospective Randomized Controlled Study on Treatment of Stage T1-3N0M0 Middle-Lower Section Esophageal Cancer by Two Minimally Invasive Radical Surgeries