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The colonization and infection with methicillin-resistant Staphylococcus aureus (MRSA) is a health problem of major importance in hospitals and long-term care facilities. Active decolonization measures are performed in MRSA-colonized patients; infections caused by MRSA are treated with vancomycin and other reserve antibiotics. The administration of bacteriophages could prevent the formation of MRSA biofilms. Inhibitors of wall teichoic acid biosynthesis could restore the efficacy of ß-lactam antibiotics against MRSA. A possibility to reduce MRSA colonization could be the administration of cultures of not drug-resistant Staphylococcus epidermidis or other physiological skin bacteria. Bacterial cultures should be taken regularly in order to control the descreased colonization with MRSA.

journal of infectious diseases and epidemiology

Alternative Methods for Treating MRSA-Colonized and Infected Patients: Bacteriophages, Inhibitors of Wall Teichoic Acid Biosynthesis and Cultures of Not Drug-Resistant Staphylococcus Epidermidis