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Dedifferentiation of leiomyosarcoma is a rare phenomenon that associates pleomorphic histology and loss of smooth muscle differentiation. Although the leiomyosarcoma is well known sarcoma in the uterus, and the dedifferentiated leiomyosarcoma is well recognized in the soft parts, there are only a few reports of dedifferentiation of leiomyosarcoma in the uterus. Herein we present a case of dedifferentiated uterine leiomyosarcoma and discuss its relation to the undifferentiated uterine sarcoma.

A Case of Dedifferentiated Leiomyosarcoma of the Uterus