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Although hot flashes and disturbed sleep receive the most attention during reproductive aging, other concerns such as depression, weight gain, fatigue and hair loss also cause women to go to the doctor. In this cohort, African American and Caucasian women with two distinct forms of cicatricial hair loss had increased risk of hypertension as compared to their respective control groups. Hypertension has a strong association with the renin-angiotensin-aldosterone system (RAAS). RAAS participates in the generation of fibrosis. The co-occurrence of cicatricial hair loss and hypertension in women may have overlapping biologic origins.

Hypertension and Cicatricial Hair Loss: Defining High Value Symptom Clusters within Reproductive Aging