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The aging process is complex and affects a variety of functions, including lower defense capability of the immune system. The immune activity, as most of physiological functions, decreases with age. The principal alterations in humoral immune response are associated with concentration of immunoglobulins, amount and activity of B cells and also the changes in the affinity of the antibodies. The current study aimed to analyze the levels of IgG and IgM antibodies of elderly and young people and to investigate thestatistical differencebetween the groups. The research was a descriptive study and contained young people and elderly from Brazil. The participants of the study were selected randomly through an interview and received medical consultation because patients who presented any pathology that result in commitment of the immune system was excluded. In the present study were evaluated a total of 70 people. After dosing immunoglobulins, a significant decrease of immunoglobulin IgM and an increase of immunoglobulin IgG were observed in elderly. Therefore, we can conclude that this study was important since it was observed that the old individuals has a differences in the levels of IgM and IgG antibodies when it is compared with young people. Based on these facts, we can justify the inability of older peopleto respond adequatelyto new infectionsand their reduced capacity to be immunized against new antigens.

Analyze the Levels of Immunoglobulins IgG and IgM in Elderly and Youngs