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The involvement of the reticuloendothelial system in systemic lupus erythematosus (SLE) concomitant to the disease activity is highly variable, and well-recognised but spontaneous splenic rupture is an unusual occurrence. We report a 35-year-old woman with SLE who had spontaneous splenic rupture during the course of her illness. The spleen rupture was evident on histophatological analysis. A brief review of spontaneous splenic rupture in systemic lupus erythematosus (SLE) is also presented. Knowledge of this condition allows the identification of risk factors and the patients characteristics with this rare disease; and can help in early diagnosis and proper treatment.

Spontaneous Spleen Rupture: An Unusual Involvement of the Spleen in Systemic Lupus Erythematosus