English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Objective quantitative evaluation for the extent of fibrosis has been introduced using CT densitometry in patients with interstitial lung diseases, however, there have been no definitive attenuation cut-off values to evaluate the extent of ground-glass opacity and fibrosis separately. This study was conducted to investigate the relationships between quantitative CT measurements using different attenuation ranges and visual CT scores, and to determine whether the different attenuation ranges can estimate the extent of ground-glass opacity and fibrosis separately in patients with pulmonary fibrosis. Methods: This study included 40 pulmonary fibrosis patients. The extent of an interstitial lesion was defined as a high attenuation area (HAA) using thresholds with pixels between 0 and −700 HU, and the extent of fibrosis was obtained by calculating the mean percentage HAA for the whole lung (%HAA0/-700). Likewise, the mean percentage HAA of different attenuation ranges, between -500 and -700 HU and between 0 and -500 HU, were obtained (%HAA-500/-700, and %HAA0/-500, respectively). The extents of ground-glass opacity and lung fibrosis were evaluated visually. The correlations of the %HAAs and visual scores were evaluated using Spearman rank correlation coefficients. Results: There were significant correlations between the mean %HAA0/-700 and the overall extent of interstitial lung lesions (ρ = 0.911, p < 0.0001). The mean %HAA0/-500 had a high correlation coefficient with fibrosis (ρ = 0.751, p < 0.0001). The mean %HAA500/-700 had a high correlation coefficient with ground-glass opacity (ρ = 0.739, p < 0.0001). Conclusion: Different attenuation ranges can be used to estimate the extent of ground-glass opacity and fibrosis separately.

Objective Quantitative CT Evaluation using Different Attenuation Ranges in Patients with Pulmonary Fibrosis: Correlations with Visual Scores