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Sentinel Node Biopsy (SNB) is used to accurately assess axillary lymph node status in patients with node-negative breast cancer. The purpose of this study was to assess the association between Non-Sentinel Node (SN) metastasis and clinicopathological findings in patients with one or two SN-positive breast cancer. We evaluated 132 patients with one or two SN-positive breast cancer and 25 patients (19%) had metastatic nonSNs. Positive non-SN metastasis was associated with the HER2 positive (P = 0.035), tumor size (P = 0.06) and equal number of excisional SN and positive SN (P = 0.003). When considering omitting the dissection in SN-positive patients, it is essential to carefully consider the number of removed SNs. Moreover, particular caution is required when considering whether to omit the dissection in patients with tumors exhibiting diameters of > 2 cm or HER2overexpressing.

The Omission of Axillary Lymph Node Dissection in Sentinel Node-Positive Breast Cancer Patients Requires Careful Consideration