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Purpose: To analyze the prognostic effects of our selecting surgical procedures for gallbladder carcinoma based on the extent of tumor invasion. Methods: We reviewed 35 patients with gallbladder carcinoma who underwent the surgical treatment in our hospital. We divided the patients into three groups (8 with T1, 15 with T2, and 12 patients with T3) according to the pathological extent of the tumor invasion. Results: Although 8 patients with T1 group had been achieved curative operation (R0), 2 patients developed an unexpected recurrence regardless the kinds of surgical procedures. Regarding the 15 patients in T2, the prognosis of 11 patients with T2n- was satisfactory. Of the 4 patients with T2n+, only 3 patients who underwent an extent cholecystectomy (ExC) and lymph node dissection (LND) with Extra Hepatic Bile Duct Resection (EHBDR) had no recurrence. Of the 12 patients in T3, 5 patients were under the limited operation. Although, remaining 6 patients were expected to achieve curative operation (R0), all patients died. Conclusions: Our data indicated ExC+LND with the EHBDR achieved survival cases in T1/T2 group who had an expected LN metastasis. However, all patients in the T3 group died from distant metastases and peritoneal disseminations, suggesting that the surgical treatment is insufficient to overcome T3 gallbladder

international journal of surgery research and practice

A Surgical Procedure and Prognosis for Gallbladder Carcinoma According to the Extent of the Tumor Invasion -A Retrospective Case Series Study at a Japanese Hospital