English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The novel coronavirus causes severe acute respiratory syndrome 2, and can infect any population. With the currently available information on the behavior of the pandemic, we conclude that the virus has come to stay. It is clear that the most aggressive behavior and worst outcome of the infection occurs in already established risk groups, such as those with cardiovascular disease. Those with congenital heart disease make up a special risk group. Due to this group’s high heterogeneity and the paucity of published cases related to coronavirus infection, its ultimate behavior cannot yet be known. Based on the anatomical and hemodynamic abnormalities with systemic repercussions which accompany congenital heart disease, this review was carried out with the aim of describing and analyzing this population’s risk factors and potentially increased vulnerability to coronavirus infection. Systemic hematological abnormalities, along with the prothrombotic state, proinflammatory state, and altered immune response in cyanotic congenital heart disease are highlighted; along with the arrhythmias, pulmonary hypertension, underlying heart failure and target organ damage, among others, present in unrepaired congenital heart disease. This review searched for articles in PubMed, Science Direct, SciELO, MD Consult and Google Scholar using the MeSH terms “coronavirus disease 2019”, “COVID-19”, “SARS-CoV-2 pandemic”, “coronavirus and cardiovascular system”, “congenital heart diseases”, “hematologic disorders in congenital heart disease”, and “pro-inflammatory mediators”. Finally, a brief description of the collateral effects of the pandemic on the care of this population is provided.

Impact of the SARS-Cov-2 Virus Pandemic on Children and Adults with Congenital Heart Disease: Its Burden and Risk Factors