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Case report of a 33-year-old G5P3+1SA diagnosed with an intrauterine foetal death at 36 weeks gestation and induction of labour started with 400 ug of misoprostol vaginally, which was complicated by a uterine rupture with subsequent referral and management in our facility. Intra-operative findings during laparotomy revealed uterine rupture with a macerated still birth intra-abdominally and moderate hemoperitoneum. Uterine rupture in an unscarred uterus following unsuccessful induction is an adverse effect that needs to be monitored and also requiring high index of suspicion to be diagnosed. A missed diagnosis of a uterine rupture during induction of labour could result in maternal mortality due to shock from severe hemoperitoneum. Incidence of uterine rupture following misoprostol induction is rarely recorded due to its use in gynaecological practice which has been off label, hence there is need to document this occurrence experienced in our facility.

Uterine Rupture Following Misoprostol Induction of Labour at 36 Weeks Gestation in an Unscarred Uterus